Dilated Cardiomyopathy Panel, Sequencing
Ordering Recommendation
Use to determine etiology of dilated cardiomyopathy (DCM) in symptomatic individuals. Useful for presymptomatic testing in individuals with family history of DCM or sudden cardiac death.
New York DOH Approval Status
Specimen Required
Lavender (EDTA) or yellow (ACD solution A or B).
New York State Clients: Lavender (EDTA)
Transport 3 mL whole blood. (Min: 1.5 mL)
New York State Clients: 8 mL (Min: 4 mL)
Refrigerated.
Serum or plasma, grossly hemolyzed or frozen specimens.
Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: Unacceptable
New York State Clients: Ambient: 72 hours; Refrigerated: 1 week; Frozen: Unacceptable
Methodology
Massively Parallel Sequencing
Performed
Varies
Reported
10-15 days
Reference Interval
By report
Interpretive Data
Refer to report.
Laboratory Developed Test (LDT)
Note
Genes tested: ABCC9, ACTC1, ACTN2, ALMS1, BAG3, CRYAB, CSRP3, DES, DMD, DOLK, DSC2, DSG2, DSP, EMD, FKTN, FLNC*, GLA, JUP, LAMP2, LDB3, LMNA, MYBPC3, MYH6, MYH7, MYL2, MYL3, PKP2, PLN, PRDM16, PRKAG2*, RAF1, RBM20, RYR2, SCN5A, SGCD, TAZ, TCAP, TMEM43, TNNC1, TNNI3, TNNT2, TPM1, TTN*, TTR, VCL.
* One or more exons are not covered by sequencing for the indicated gene; see Additional Technical Information.
Hotline History
CPT Codes
81439
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
3001582 | Dilated Cardiomyopathy Interp | |
3001670 | Dilated Cardiomyopathy Specimen |
Aliases
- DCM
- familial dilated cardiomyopathy (FDCM)